BBC has a story about research on using modified tsetse fly gut bacteria against it. There were 7000 new cases in 2010, making it one of the smaller killers—but nasty nonetheless; the disease is fatal and so are O(5-20%) of the cures.
A few small details: It is a plan but not a procedure. How do you infect the flies? If they die they may not be able to infect each other or the next generation. And do those gut bacteria get into people?